姓名:郑操
籍贯:湖北 仙桃
职称:副教授
学位:博士
职务:生物工程专业负责人
E-mail:zhengc1314@163.com
一、个人简介
郑操,男,1988年生,博士,副教授。湖北生物工程学会理事,中国微生物学会会员。2009年6月毕业于华中农业大学,获工学学士学位;2015年6月毕业于华中农业大学,获理学博士学位。主要从事微生物代谢调控方面的研究。
二、科研项目
1.国家自然科学基金(31700069):蜡状芽胞杆菌群中c-di-AMP新型候选受体蛋白PrpD的功能及其调控芽胞形成的分子机制研究,2018.01-2020.12,主持完成。
2.湖北省教育厅中青年人才项目(Q20171707):透明颤菌血红蛋白对裂壶藻合成DHA的作用,2017.01-2018.12,主持完成。
三、研究论文(*通信作者)
1.Cao Zheng, Zhaoqing Yu, Cuiying Du, Yujing Gong, Wen Yin, Xinfeng Li, Zhou Li, Ute Römling, Shan-Ho Chou, Jin He*. 2-Methylcitrate cycle: a well-regulated controller of Bacillus sporulation. Environmental Microbiology, 2020, 22: 1125-1140.
2.Wanqian Yan, Xinyuan Mao, Yujun Dai, Lihua Wang, Cuiying Du*, Cao Zheng*. Enzymatic characterization of TbrA, the first identified aconitate isomerase from Bacillus thuringiensis. Acta Microbiologica Sinica, 2021, 61: 388-397.
3.Jie Fu, Tao Chen, Hao Lu, Yuanfeng Lin, Xinlei Xie, Hua Tian, Cao Zheng*, Dongping He. Enhancement of docosahexaenoic acid production by low-energy ion implantation coupled with screening method based on Sudan black B staining in Schizochytrium sp. Bioresource Technology, 2016, 221: 405-411.
4.Hang Zhou#, Cao Zheng#, Jianmei Su#, Bo Chen, Yang Fu, Yuqun Xie, Qing Tang, Shan-Ho Chou, Jin He. Characterization of a natural triple-tandem c-di-GMP riboswitch and application of the riboswitch-based dual-fluorescence reporter. Scientific Reports, 2016, 6: 20817.
5.Cao Zheng, Yang Ma, Xun Wang, Yuqun Xie, Maria Kanwal Ali, Jin He. Functional analysis of the sporulation-specific disdenylate cyclase CdaS in Bacillus thuringiensis. Frontiers in Microbiology, 2015, 6: 908.
6.Cao Zheng, Jieping Wang, Yunchao Luo, Yang Fu, Jianmei Su, Jin He. Highly efficient enzymatic preparation of c-di-AMP using the diadenylate cyclase DisA from Bacillus thuringiensis. Enzyme and Microbial Technology, 2013, 52 (6-7): 319-324.
7.Cao Zheng, Jing Zhao, Peng Bao, Jin Gao, Jin He. Dispersive liquid-liquid microextraction based on solidification of floating organic droplet followed by high-performance liquid chromatography with ultraviolet detection and liquid chromatography-tandem mass spectrometry for the determination of triclosan and 2,4-dichlorophenol in water samples. Journal of Chromatography A, 2011, 1218 (25): 3830-3836.
8.都萃颖, 吴菲, 严婉芊, 戴余军, 王立华, 郑操*. 细菌中2-甲基柠檬酸循环研究进展, 微生物学通报, 2020, 47: 1582-1588.
9.郑操, 蔡鹭, 张中强, 王立华, 戴余军, 都萃颖. 土壤中可编码乌头酸异构酶的芽胞杆菌菌株筛选及鉴定. 微生物学报, 2019, 59: 1373-1382.
10.Jieping Wang, Han Mei, Cao Zheng, Hongliang Qian, Cui Cui, Yang Fu, Jianmei Su, Ziduo Liu, Ziniu Yu, Jin He. The metabolic regulation of sporulation and parasporal crystal formation in Bacillus thuringiensis revealed by transcriptomics and proteomics. Molecular and Cellular Proteomics, 2013, 12(5): 1363-1376.
11.Qing Tang, Yunchao Luo, Cao Zheng, Kang Yin, Maria Kanwal Ali, Xinfeng Li, Jin He. Functional Analysis of a c-di-AMP-specific Phosphodiesterase MsPDE from Mycobacterium smegmatis. International Journal of Biological Sciences, 2015, 11(7): 813-824.
12.Hang Yang, Jin He, Fen Hu, Cao Zheng, Ziniu Yu. Detection of Escherichia coli enoyl-ACP reductase using biarsenical-tetracysteine motif. Bioconjugate Chemistry, 2010, 21(7): 1341-1348.
四、教学成果(含课程建设、教学研究、教材编写等)
1. 湖北省高等学校省级教学研究项目:新工科背景下地方应用型高校生物工程专业人才创新创业能力培养探索与实践,2021.06-2024.05,项目主持人。
五、指导学生科研立项、获奖
1. 指导学生获全国大学生生命科学竞赛(2021,科学探究类)二等奖. 2021年11月.
2. 指导学生获湖北省第六届大学生生物实验技能竞赛(综合赛)一等奖. 2019年11月.